SP866FAVORABLE RENAL SURVIVAL IN PEDIATRIC MICROSCOPIC POLYANGITIS: EFFICACY OF A NOVEL TREATMENT ALGORITHM
نویسندگان
چکیده
منابع مشابه
Favourable renal survival in paediatric microscopic polyangiitis: efficacy of a novel treatment algorithm.
BACKGROUND Microscopic polyangiitis (MPA) is one of the most common forms of antineutrophil cytoplasm autoantibodies (ANCA)-associated vasculitis in children. Cyclophospamide and glucocorticoid-based treatment protocols are still considered gold standard in managing this multi-system disorder. But treatment-related toxicity is a major cause of chronic morbidity and early mortality in MPA. Hence...
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Microscopic polyangiitis (MPA) is a form of anti neutrophilic cytoplasmic antibody associated necrotizing vasculitis, which may present with a variety of clinical manifestations. Cardiac involvement in vaculitis is common and the manifestations usually include cardiomyopathy, pericarditis and arrhythmias. Our patient presented with dyspnea, hemoptysis and acute kidney injury. The patient develo...
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Anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) is a group of rare autoimmune diseases. Although the aetiology of AAV is uncertain, it is likely that genetic and environmental factors contribute. We report the unusual case of two brothers presenting with AAV with differing clinical pictures and differing ANCA specificity. There is a recently identified difference in geneti...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2015
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/gfv203.04